SCHEMBL7733600

SCHEMBL7733600

CC(C)(C)c1ccc([I+]c2ccc(C(C)(C)C)cc2)cc1.Cc1cc(-c2ccccc2)ccc1S(=O)(=O)[O-]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 1/20 0.44
DHODH Q02127 1/20 0.39
LMNA P02545 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 1/20 0.36
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
MAPK1 P28482 1/20 0.36
RECQL P46063 1/20 0.36
HSD17B10 Q99714 1/20 0.36
RXRB P28702 2/20 0.36
PTPN1 P18031 1/20 0.36
RXRA P19793 1/20 0.36
MAPT P10636 1/20 0.35
HTR6 P50406 1/20 0.35
HSD11B1 P28845 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175822 0.82 HSD11B1 (0.43) HSD17B2LMNANPSR1ALDH1A1ALOX15
Biphenyl SCHEMBL1360704 0.77 PTPN1 (0.43) HSD17B2ALDH1A1RECQLPTPN1MAPT
SCHEMBL452774 0.76 ALDH1A1 (0.46) HSD17B2LMNAALDH1A1RECQLMAPT
Sulfuric Acid SCHEMBL5068665 0.73 ALDH1A1 (0.52) LMNANPSR1ALDH1A1CYP3A4HPGD
SCHEMBL217706 0.73 ALDH1A1 (0.48) LMNANPSR1ALDH1A1CYP3A4HPGD
SCHEMBL7738075 0.72 NR3C2 (0.50) HSD17B2LMNAALDH1A1CYP3A4RECQL
SCHEMBL2966140 0.72 HSD11B1 (0.43) HSD17B2ALDH1A1HSD11B1
SCHEMBL8131241 0.72 ALDH1A1 (0.52) LMNANPSR1ALDH1A1CYP3A4HPGD
Sulfuric Acid SCHEMBL482026 0.72 ALDH1A1 (0.50) LMNANPSR1ALDH1A1CYP3A4HPGD
SCHEMBL1718940 0.72 ALDH1A1 (0.50) LMNANPSR1ALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6416928-B1 HALOGENONIUM OR SULFONIUM SALTS OF SULFONATED DIPHENYLALKANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-07-09 US disclosed