SCHEMBL7733730

SCHEMBL7733730

COCCN(C)c1ccccc1N(C)CCOC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
TP53 P04637 1/20 0.41
TSHR P16473 3/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
SLC40A1 Q9NP59 1/20 0.38
LMNA P02545 2/20 0.38
PIK3CD O00329 1/20 0.35
HTR7 P34969 1/20 0.35
CRHR1 P34998 1/20 0.35
CYP1A2 P05177 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
ADRA2A P08913 1/20 0.34
CYP2D6 P10635 1/20 0.34
CHRM1 P11229 1/20 0.34
ADRA2B P18089 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6223613 0.83 ALDH1A1 (0.43) KMT2AMEN1TP53TSHRALDH1A1
SCHEMBL4744589 0.82 GAA (0.38) KMT2AMEN1TP53TSHRALDH1A1
SCHEMBL22738379 0.80 KMT2A (0.39) KMT2AMEN1TP53ALDH1A1SLC40A1
SCHEMBL7243914 0.80 MEN1 (0.44) KMT2AMEN1ALDH1A1LMNAHTR7
SCHEMBL21590304 0.79 ALDH1A1 (0.45) KMT2AMEN1ALDH1A1KDM4ELMNA
SCHEMBL7723639 0.78 ALOX15 (0.37) TSHRALDH1A1KDM4ELMNACYP1A2
SCHEMBL7731805 0.77 CHRM2 (0.37) TSHRALDH1A1KDM4ELMNAHTR7
SCHEMBL18562081 0.76 BRAF (0.41) KMT2AMEN1TSHRALDH1A1HPGD
SCHEMBL9060715 0.76 SIGMAR1 (0.43) KMT2AMEN1TP53TSHRCYP2D6
SCHEMBL9424530 0.76 SIGMAR1 (0.43) KMT2AMEN1TP53TSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399272-B1 Phenylenediamine derivative-type additive useful for a chemically amplified photoresist HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-06-04 US disclosed