Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735232 | 0.95 | THRA (0.41) | THRATHRBGABRA1GABRB2L3MBTL1 | |
| SCHEMBL7725078 | 0.89 | GABRA1 (0.40) | GABRA1GABRB2SOAT1HDAC8 | |
| SCHEMBL7734873 | 0.85 | THRA (0.46) | THRATHRBLMNAL3MBTL1FFAR1 | |
| SCHEMBL7735387 | 0.81 | THRA (0.41) | THRATHRBFFAR1FFAR4SOAT1 | |
| SCHEMBL7734115 | 0.81 | THRA (0.54) | THRATHRBFFAR1FFAR4KDM4E | |
| SCHEMBL7734916 | 0.80 | NR3C1 (0.44) | THRATHRBFFAR4KDM4E | |
| SCHEMBL7734876 | 0.78 | THRA (0.47) | THRATHRBLMNAL3MBTL1FFAR1 | |
| SCHEMBL7735380 | 0.77 | PTPN1 (0.44) | THRATHRBHDAC8KDM4E | |
| SCHEMBL7734923 | 0.77 | THRA (0.43) | THRATHRBFFAR1FFAR4KDM4E | |
| SCHEMBL7725105 | 0.76 | FFAR4 (0.46) | THRATHRBLMNAFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | claimed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | claimed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |