Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734916 | 0.95 | NR3C1 (0.44) | THRATHRBNR3C1FFAR4KDM4E | |
| SCHEMBL7735380 | 0.92 | PTPN1 (0.44) | THRATHRBKDM4E | |
| SCHEMBL7735362 | 0.89 | PTPN1 (0.39) | NR3C1KDM4E | |
| SCHEMBL7733974 | 0.85 | THRA (0.47) | THRATHRBFFAR1FFAR4LMNA | |
| SCHEMBL27430965 | 0.82 | FFAR4 (0.39) | FFAR4KDM4E | |
| SCHEMBL7725082 | 0.81 | THRA (0.53) | THRATHRBNR3C1FFAR1TDP1 | |
| SCHEMBL7735232 | 0.80 | THRA (0.41) | THRATHRBFFAR1FFAR4L3MBTL1 | |
| SCHEMBL7735387 | 0.79 | THRA (0.41) | THRATHRBFFAR1FFAR4KDM4E | |
| SCHEMBL7734876 | 0.79 | THRA (0.47) | THRATHRBFFAR1FFAR4LMNA | |
| SCHEMBL3403005 | 0.76 | NR3C1 (0.43) | THRATHRBNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | claimed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | claimed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | claimed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | claimed |
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | disclosed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |