Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734854 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1BHTR2AHTR2C | |
| SCHEMBL6364152 | 0.76 | HTR2A (0.63) | MTNR1AMTNR1BHTR2AHTR2C | |
| SCHEMBL5796602 | 0.65 | KDM4E (0.39) | MTNR1AMTNR1BHTR2AHTR2C | |
| SCHEMBL5232827 | 0.63 | KDM4E (0.47) | — | |
| SCHEMBL3899800 | 0.63 | HTR2A (0.43) | HTR2AHTR2C | |
| SCHEMBL3702253 | 0.61 | MPO (0.62) | HTR2A | |
| SCHEMBL23302470 | 0.60 | PARP1 (0.37) | — | |
| SCHEMBL3578553 | 0.59 | LMNA (0.45) | — | |
| SCHEMBL3597833 | 0.59 | KDM4E (0.41) | — | |
| SCHEMBL5637174 | 0.59 | HTR2A (0.55) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828325-B2 | A benzoxazolopiperazine derivative useful for treating Parkinson's diseases, schizophrenia, anxiety and depression | SOLVAY PHARMACEUTICALS B.V. (CH) | 2004-12-07 | — | — | US | disclosed |