Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357414 | 0.84 | ALDH1A1 (0.54) | SRCALDH1A1L3MBTL1GAAKDM4E | |
| SCHEMBL24025600 | 0.84 | PSMB5 (0.37) | SRCCYP2A6CYP2A13PSMB5PTGS2 | |
| SCHEMBL9806957 | 0.78 | SRC (0.75) | SRCPTGS2ALDH1A1GAAKDM4E | |
| SCHEMBL5535026 | 0.76 | G6PD (0.49) | SRCALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL10714143 | 0.76 | SRC (0.53) | SRCALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9200244 | 0.75 | SLC16A3 (0.45) | CYP2A6CYP2A13PTGS2ALDH1A1L3MBTL1 | |
| SCHEMBL23241447 | 0.75 | RXRA (0.49) | SRCALDH1A1L3MBTL1GAAKDM4E | |
| SCHEMBL31561376 | 0.74 | HSD17B10 (0.64) | SRCALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9090045 | 0.74 | HSD17B10 (0.64) | SRCALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10515797 | 0.73 | SLC16A3 (0.44) | SRCALDH1A1L3MBTL1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218182-B | IDO inhibitors | 南京亘泰医药技术有限公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-110218182-A | IDO inhibitor | 南京亘泰医药技术有限公司 | 2019-09-10 | — | — | CN | disclosed |
| US-6420181-B1 | DETECTING PREFERENTIAL PARTICLE IN SOLUTION; OBTAIN SOLUTION CONTAINING PARTICLE, MIX WITH SOLVENT, INSERT INTO TUBE, INCUBATE WITH CHROMOGENIC DETECTION INDICATOR, MONITOR SAMPLE FOR SIGNAL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2002-07-16 | — | — | US | disclosed |