Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734873 | 0.82 | THRA (0.46) | FFAR4KDM4E | |
| SCHEMBL27402109 | 0.82 | S1PR1 (0.40) | FFAR4GPR88P2RY12KDM4ES1PR1 | |
| SCHEMBL7734916 | 0.81 | NR3C1 (0.44) | FFAR4TRPV1KEAP1KDM4ESLC2A1 | |
| SCHEMBL27406922 | 0.80 | PTGS2 (0.41) | FFAR4GPR88 | |
| SCHEMBL27430017 | 0.78 | THRA (0.49) | KDM4E | |
| SCHEMBL7735380 | 0.77 | PTPN1 (0.44) | ADRB3CA12CA9TRPV1KDM4E | |
| SCHEMBL7735362 | 0.76 | PTPN1 (0.39) | ADRB3CA12CA9TRPV1KDM4E | |
| SCHEMBL27406916 | 0.75 | THRA (0.53) | KDM4E | |
| SCHEMBL27539979 | 0.70 | KDM4E (0.45) | KDM4E | |
| SCHEMBL27428212 | 0.69 | SLC6A9 (0.44) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | disclosed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | disclosed |