Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10704484 | 0.89 | PTPN1 (0.46) | PTPN1BACE1ALOX5OR51E2APP | |
| SCHEMBL7737580 | 0.89 | PTPN1 (0.60) | PTPN1BACE1ALOX5OR51E2APP | |
| SCHEMBL3685390 | 0.83 | CCNC (0.58) | PTPN1BACE1ALOX5OR51E2APP | |
| SCHEMBL7725329 | 0.81 | GAA (0.43) | PTPN1BACE1ALOX5OR51E2GABRA1 | |
| 4-Hydroxyhydrocinnamic Acid Methyl Ester SCHEMBL95254 | 0.81 | HDAC2 (0.53) | HDAC2HDAC8ALDH1A1GAAMEN1 | |
| SCHEMBL7725121 | 0.81 | BACE1 (0.55) | PTPN1BACE1ALOX5APPHPGD | |
| SCHEMBL3274537 | 0.80 | APP (0.68) | ALOX5OR51E2APPALDH1A1GFER | |
| 4-Hydroxyhydrocinnamic Acid Methyl Ester SCHEMBL30611554 | 0.80 | HDAC2 (0.51) | HDAC2HDAC8ALDH1A1GAAMEN1 | |
| SCHEMBL12646568 | 0.79 | HCAR2 (0.55) | PTPN1APPALDH1A1HPGDHSD17B10 | |
| SCHEMBL3687535 | 0.79 | ENPP2 (0.44) | PTPN1BACE1ALOX5OR51E2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |