Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962122 | 0.85 | MAOB (0.51) | MAOBMAOAMRGPRX4ALDH1A1IL4I1 | |
| SCHEMBL18412078 | 0.85 | ALDH1A1 (0.46) | MRGPRX4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13513257 | 0.85 | MAOB (0.51) | MAOBMAOAMRGPRX4ALDH1A1IL4I1 | |
| SCHEMBL27754882 | 0.83 | FOLH1 (0.61) | MRGPRX4CYP2D6HPGDSMN1; SMN2 | |
| SCHEMBL1706376 | 0.83 | MAOB (0.54) | MAOBMRGPRX4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL4191880 | 0.82 | CTBP2 (0.44) | ALDH1A1 | |
| SCHEMBL4558230 | 0.81 | MAOB (0.49) | MAOBMAOAMRGPRX4ALDH1A1IL4I1 | |
| SCHEMBL6155568 | 0.81 | MAOB (0.51) | MAOBMAOAMRGPRX4ALDH1A1IL4I1 | |
| SCHEMBL1492354 | 0.81 | LOXL2 (0.66) | MRGPRX4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3335985 | 0.80 | LMNA (0.59) | MAOBMAOAMRGPRX4ALDH1A1IL4I1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403622-B1 | FOR CONTROLLING INSECTS, ARACHNIDS, NEMATODES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-11 | — | — | US | disclosed |
| CN-1329611-A | Phenylacetic acid heterocyclyl amides having an insecticidal effect | BAYER AG (DE) | 2002-01-02 | — | — | CN | disclosed |