Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735368 | 0.95 | THRB (0.41) | TSHRTHRBSLC6A4SLC6A3TAAR1 | |
| SCHEMBL14749530 | 0.95 | THRB (0.41) | TSHRTHRBSLC6A4SLC6A3TAAR1 | |
| SCHEMBL7733396 | 0.93 | TSHR (0.45) | TSHRTHRBSLC6A4SLC6A3EPHX2 | |
| SCHEMBL7732792 | 0.93 | TSHR (0.45) | TSHRTHRBSLC6A4SLC6A3EPHX2 | |
| SCHEMBL7735489 | 0.92 | TSHR (0.44) | TSHRTHRBSLC6A4SLC6A3EPHX2 | |
| SCHEMBL14749515 | 0.91 | TSHR (0.44) | TSHRSLC6A4SLC6A3EPHX2NR1H4 | |
| SCHEMBL7735170 | 0.91 | TSHR (0.44) | TSHRSLC6A4SLC6A3EPHX2NR1H4 | |
| SCHEMBL7729811 | 0.90 | FAAH (0.41) | TSHRTHRBSLC6A4SLC6A3KMT2A | |
| SCHEMBL7731398 | 0.90 | TAAR1 (0.46) | TAAR1KMT2AMAOBPSMB5 | |
| SCHEMBL7729682 | 0.90 | TSHR (0.45) | TSHRSLC6A4SLC6A3TAAR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |