Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735368 | 1.00 | THRB (0.41) | THRBTSHRMAOBALDH1A1TAAR1 | |
| SCHEMBL7731398 | 0.95 | TAAR1 (0.46) | MAOBTAAR1PSMB5PPARAPPARD | |
| SCHEMBL7732792 | 0.95 | TSHR (0.45) | THRBTSHRALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL7730387 | 0.95 | TAAR1 (0.46) | MAOBTAAR1PSMB5PPARAPPARD | |
| SCHEMBL7733396 | 0.95 | TSHR (0.45) | THRBTSHRALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL7735178 | 0.95 | TSHR (0.39) | THRBTSHRMAOBALDH1A1TAAR1 | |
| SCHEMBL7735489 | 0.93 | TSHR (0.44) | THRBTSHRALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL7731366 | 0.93 | FAAH (0.39) | THRBALDH1A1PLK1PPARAMEN1 | |
| SCHEMBL7733321 | 0.93 | BCHE (0.40) | THRBTSHRMAOBALDH1A1TAAR1 | |
| SCHEMBL7731801 | 0.93 | TAAR1 (0.44) | MAOBTAAR1PSMB5PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822305-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-21 | — | — | US | disclosed |
| US-9809749-B2 | Mesogenic compound, liquid-crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-9612445-B2 | Lens element | MERCK PATENT GMBH (DE) | 2017-04-04 | — | — | US | disclosed |
| US-9475990-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2016-10-25 | — | — | US | disclosed |
| US-20160115388-A1 | MESOGENIC COMPOUND, LIQUID-CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2016-04-28 | — | — | US | disclosed |
| US-9315729-B2 | Polymerizable compounds and their use in liquid crystal media and liquid crystal displays | MERCK PATENT GMBH (DE) | 2016-04-19 | — | — | US | disclosed |
| US-20150301344-A1 | LENS ELEMENT | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150247089-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-09-03 | — | — | US | disclosed |
| US-9120969-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2015-09-01 | — | — | US | disclosed |
| US-20140225035-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140158934-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-06-12 | — | — | US | disclosed |
| US-20140125938-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID CRYSTAL MEDIA AND LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-05-08 | — | — | US | disclosed |
| US-20140077130-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-03-20 | — | — | US | disclosed |
| US-8659737-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2014-02-25 | — | — | US | disclosed |
| WO-2013156113-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2013-10-24 | — | — | WO | disclosed |
| US-20130057947-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140125938-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID CRYSTAL MEDIA AND LIQUID CRYSTAL DISPLAYS | LPXN, BPHL, MAP1LC3C | THRB 4802/4885TSHR 4818/4885MAOB 1838/4885 |
| US-20160115388-A1 | MESOGENIC COMPOUND, LIQUID-CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | BMP2, IK, EML4 | THRB 3904/4885TSHR 4680/4885MAOB 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.