Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14749530 | 1.00 | THRB (0.41) | THRBTSHRMAOBALDH1A1TAAR1 | |
| SCHEMBL7731398 | 0.95 | TAAR1 (0.46) | MAOBTAAR1PSMB5PPARAPPARD | |
| SCHEMBL7732792 | 0.95 | TSHR (0.45) | THRBTSHRALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL7730387 | 0.95 | TAAR1 (0.46) | MAOBTAAR1PSMB5PPARAPPARD | |
| SCHEMBL7733396 | 0.95 | TSHR (0.45) | THRBTSHRALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL7735178 | 0.95 | TSHR (0.39) | THRBTSHRMAOBALDH1A1TAAR1 | |
| SCHEMBL7735489 | 0.93 | TSHR (0.44) | THRBTSHRALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL7731366 | 0.93 | FAAH (0.39) | THRBALDH1A1PLK1PPARAMEN1 | |
| SCHEMBL7733321 | 0.93 | BCHE (0.40) | THRBTSHRMAOBALDH1A1TAAR1 | |
| SCHEMBL7731801 | 0.93 | TAAR1 (0.44) | MAOBTAAR1PSMB5PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |