Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CTSA | P10619 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.51 |
| ▸ | WNT3A | P56704 | 3/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737426 | 0.89 | KMT2A (0.50) | SMN1; SMN2LMNARAB9AHPGDALDH1A1 | |
| SCHEMBL14241376 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP1A2LMNARAB9AHPGD | |
| SCHEMBL17485108 | 0.84 | CTSA (0.50) | SMN1; SMN2LMNARAB9AHPGDALDH1A1 | |
| SCHEMBL402416 | 0.82 | CA12 (0.62) | LMNARAB9AALDH1A1CTSAKMT2A | |
| SCHEMBL1527427 | 0.82 | CTNNB1 (0.73) | CYP1A2HPGDALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL29923058 | 0.82 | CTNNB1 (0.73) | CYP1A2HPGDALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL9524595 | 0.80 | SYK (0.63) | SMN1; SMN2LMNAALDH1A1CTSAKMT2A | |
| SCHEMBL11710256 | 0.80 | CTSA (0.49) | SMN1; SMN2LMNARAB9AHPGDALDH1A1 | |
| SCHEMBL5188941 | 0.79 | ALDH1A1 (0.59) | CYP1A2HPGDALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL35823 | 0.79 | PTGS2 (0.58) | SMN1; SMN2LMNARAB9AHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |