Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CTSA | P10619 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.49 |
| ▸ | WNT3A | P56704 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735238 | 0.89 | SMN1; SMN2 (0.55) | KMT2ASMN1; SMN2MAPTHPGDCTSA | |
| SCHEMBL14241376 | 0.83 | SMN1; SMN2 (0.60) | KMT2ASMN1; SMN2MAPTHPGDCTSA | |
| SCHEMBL17485108 | 0.82 | CTSA (0.50) | KMT2ASMN1; SMN2MAPTHPGDCTSA | |
| SCHEMBL11710256 | 0.80 | CTSA (0.49) | KMT2ASMN1; SMN2MAPTHPGDCTSA | |
| SCHEMBL35823 | 0.80 | PTGS2 (0.58) | KMT2ASMN1; SMN2MAPTCTSAALDH1A1 | |
| SCHEMBL10001233 | 0.79 | SMN1; SMN2 (0.66) | KMT2ASMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL402416 | 0.79 | CA12 (0.62) | KMT2ACTSAALDH1A1LMNASYK | |
| SCHEMBL9524595 | 0.78 | SYK (0.63) | KMT2ASMN1; SMN2MAPTCTSAALDH1A1 | |
| SCHEMBL7733973 | 0.78 | THRA (0.49) | KMT2ASMN1; SMN2MAPTHPGDTHRA | |
| SCHEMBL7735763 | 0.77 | PTPN1 (0.54) | KMT2AHPGDLMNALTB4RL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |