SCHEMBL7735382

SCHEMBL7735382

CCC(O)COc1ccc(CCC(=O)O)cc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 12/20 0.48
FFAR1 O14842 11/20 0.47
TP53 P04637 2/20 0.46
MDM2 Q00987 2/20 0.46
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46
PTGDR2 Q9Y5Y4 1/20 0.45
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
CASR P41180 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KCNH2 Q12809 1/20 0.44
BCL2L1 Q07817 1/20 0.44
MCL1 Q07820 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7725085 0.93 PPARG (0.45) FFAR4FFAR1TP53MDM2PPARG
SCHEMBL7735390 0.90 PTPN1 (0.55) TP53SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL7734883 0.86 TP53 (0.52) FFAR4FFAR1TP53MDM2PPARG
SCHEMBL7734083 0.85 PTPN1 (0.48) PPARGPPARDPPARAPTGDR2KCNH2
SCHEMBL7734788 0.81 RXRA (0.53) FFAR4FFAR1PPARGPPARDPPARA
SCHEMBL7735870 0.81 PPARD (0.47) FFAR4FFAR1TP53MDM2PPARG
SCHEMBL7735506 0.81 PTGDR2 (0.63) FFAR4FFAR1TP53MDM2PTGDR2
SCHEMBL7734086 0.81 THRA (0.57) FFAR4FFAR1PPARGPPARDPPARA
SCHEMBL7734849 0.81 PTGDR2 (0.53) FFAR4FFAR1TP53MDM2PPARG
SCHEMBL7734077 0.80 PPARD (0.47) FFAR4FFAR1TP53MDM2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN claimed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US claimed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN claimed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP claimed
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN disclosed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed