Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735172 | 0.88 | SMN1; SMN2 (0.59) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL7735683 | 0.78 | PTGS1 (0.42) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL155002 | 0.76 | MAPT (1.00) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL10786285 | 0.75 | ESR1 (0.54) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| 2-Phenethylbenzo[D]Oxazole SCHEMBL10582102 | 0.75 | MAPT (0.81) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL9855739 | 0.73 | GAA (0.57) | MAPTSMN1; SMN2TP53HTTLMNA | |
| SCHEMBL284696 | 0.72 | ALDH1A1 (0.63) | MAPTSMN1; SMN2TP53HTTLMNA | |
| SCHEMBL7735679 | 0.71 | MEN1 (0.51) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| Water SCHEMBL8834363 | 0.71 | DDAH1 (0.56) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2123399 | 0.70 | MAPT (0.78) | MAPTRAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |