Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735679 | 0.80 | MEN1 (0.51) | PTGS1PTGS2ALOX5RAB9AMAPT | |
| SCHEMBL7735172 | 0.79 | SMN1; SMN2 (0.59) | RAB9AMAPTNPC1SMN1; SMN2LMNA | |
| SCHEMBL7735664 | 0.78 | MAPT (0.58) | RAB9AMAPTNPC1SMN1; SMN2LMNA | |
| SCHEMBL10786285 | 0.71 | ESR1 (0.54) | PTGS1PTGS2RAB9AMAPTNPC1 | |
| Benzene SCHEMBL27590057 | 0.70 | NPC1 (0.58) | RAB9AMAPTNPC1SMN1; SMN2LMNA | |
| SCHEMBL11229435 | 0.68 | TNFRSF1A (0.55) | PTGS1PTGS2ALOX5MAPTSMN1; SMN2 | |
| SCHEMBL10589899 | 0.68 | TNFRSF1A (0.55) | PTGS1PTGS2ALOX5MAPTSMN1; SMN2 | |
| SCHEMBL10851833 | 0.68 | BRD4 (0.43) | PTGS2RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL10851835 | 0.68 | BRD4 (0.43) | PTGS2RAB9AMAPTNPC1SMN1; SMN2 | |
| Water SCHEMBL8834363 | 0.68 | DDAH1 (0.56) | RAB9AMAPTNPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |