Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735664 | 0.88 | MAPT (0.58) | SMN1; SMN2LMNATP53RAB9AMAPT | |
| SCHEMBL6969232 | 0.81 | DHFR (0.39) | SMN1; SMN2LMNATP53MAPTKMT2A | |
| SCHEMBL7735683 | 0.79 | PTGS1 (0.42) | SMN1; SMN2LMNATP53RAB9AMAPT | |
| SCHEMBL10786285 | 0.76 | ESR1 (0.54) | SMN1; SMN2TP53RAB9AMAPTNPC1 | |
| SCHEMBL7724844 | 0.75 | TOP2A (0.47) | SMN1; SMN2LMNARAB9AMAPTNPC1 | |
| SCHEMBL4688937 | 0.75 | SMN1; SMN2 (0.83) | SMN1; SMN2LMNATP53RAB9AMAPT | |
| Water SCHEMBL8834363 | 0.74 | DDAH1 (0.56) | SMN1; SMN2TP53RAB9AMAPTNPC1 | |
| SCHEMBL4650036 | 0.74 | TP53 (0.89) | SMN1; SMN2LMNATP53RAB9AMAPT | |
| SCHEMBL1420033 | 0.74 | TP53 (0.81) | SMN1; SMN2LMNATP53RAB9AMAPT | |
| SCHEMBL1906504 | 0.72 | TP53 (0.83) | SMN1; SMN2LMNATP53RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |