Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 9/20 | 0.41 |
| ▸ | THRB | P10828 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SELL | P14151 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962364 | 0.83 | MEN1 (0.50) | THRATHRBGAAMEN1KMT2A | |
| SCHEMBL6969104 | 0.78 | GAA (0.45) | GAAMEN1KMT2AGSRSELL | |
| SCHEMBL7735144 | 0.72 | NLRP3 (0.48) | GABRA1GABRB1GAAMEN1KMT2A | |
| SCHEMBL11594811 | 0.71 | TDP1 (0.48) | GABRA1GABRB1GAAMEN1KMT2A | |
| SCHEMBL4644161 | 0.70 | GABRA1 (0.78) | GABRA1GABRB1THRATHRBGAA | |
| SCHEMBL17338050 | 0.70 | CYP3A4 (0.39) | GABRA1GABRB1MEN1KMT2A | |
| SCHEMBL4323317 | 0.69 | GSR (0.53) | GABRA1GABRB1THRATHRBGAA | |
| SCHEMBL5598871 | 0.68 | HSP90AB1 (0.59) | GABRA1GABRB1GAAMEN1KMT2A | |
| SCHEMBL3640323 | 0.68 | GABRA1 (1.00) | GABRA1GABRB1THRATHRBGAA | |
| SCHEMBL8747646 | 0.68 | GSR (0.52) | GABRA1GABRB1GAAGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |