Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.78 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640323 | 0.88 | GABRA1 (1.00) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL27919073 | 0.84 | GABRA1 (0.56) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL4136739 | 0.84 | GABRA1 (0.56) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL11475072 | 0.83 | GABRA1 (0.54) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL6682827 | 0.80 | GABRA1 (0.63) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL13997556 | 0.80 | GABRA1 (0.75) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL7068142 | 0.79 | GABRA1 (0.50) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL23063467 | 0.78 | GABRA1 (0.54) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL9967745 | 0.78 | GABRA1 (0.72) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL282221 | 0.78 | GABRA1 (0.72) | GABRA1GABRB1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994844-B1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING & MFG (US) | 2002-07-31 | — | — | EP | claimed |
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-01-02 | — | — | US | disclosed |
| EP-1244756-B2 | HIGH REFRACTIVE INDEX PRESSURE-SENSITIVE ADHESIVES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-08-20 | — | — | EP | disclosed |
| US-7335425-B2 | High refractive index pressure-sensitive adhesives | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-02-26 | — | — | US | disclosed |
| US-20070264517-A1 | HIGH REFRACTIVE INDEX PRESSURE-SENSITIVE ADHESIVES | 3M INNOVATIVE PROPERTIES COMPANY | 2007-11-15 | — | — | US | disclosed |
| US-7166686-B2 | High refractive index pressure-sensitive adhesives | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-01-23 | — | — | US | disclosed |
| US-20050272949-A1 | High refractive index pressure-sensitive adhesives | 3M INNOVATIVE PROPERTIES COMPANY | 2005-12-08 | — | — | US | disclosed |
| EP-1244756-B1 | HIGH REFRACTIVE INDEX PRESSURE-SENSITIVE ADHESIVES | 3M INNOVATIVE PROPERTIES CO (US) | 2004-10-27 | — | — | EP | disclosed |
| US-20040091729-A1 | High refractive index pressure-sensitive adhesives | 3M INNOVATIVE PROPERTIES COMPANY | 2004-05-13 | — | — | US | disclosed |
| US-6663978-B1 | Polymer of an acrylic or methacrylic acid ester containing a substituted or an unsubstituted aromatic moiety | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-16 | — | — | US | disclosed |
| WO-2001012618-A1 | DIHYDROAMINOBENZO[B]- AND [C]FURANS AS RETINOID-LIKE AGENTS | ALLERGAN SALES, INC. (US) | 2001-02-22 | — | — | WO | disclosed |
| US-6093838-A | FOR TREATING SKIN-RELATED DISEASES, INCLUDING ACTINIC KERATOSES, ARSENIC KERATOSES, ECZEMA | ALLERGAN SALES, INC. (US) | 2000-07-25 | — | — | US | disclosed |
| EP-0994844-A1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-2000014050-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-16 | — | — | WO | disclosed |
| EP-0980398-A1 | CHEMICAL COMPOSITION AND POLYMERS AND POLYMERIC MATERIALS DERIVED THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| EP-0980532-A1 | OPTICAL PRODUCT PREPARED FROM HIGH INDEX OF REFRACTION BROMINATED MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| US-5932626-A | BRIGHTNESS PROMOTING FILM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1998050340-A1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-12 | — | — | WO | disclosed |
| WO-1998050442-A1 | CHEMICAL COMPOSITION AND POLYMERS AND POLYMERIC MATERIALS DERIVED THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-12 | — | — | WO | disclosed |
| WO-1998050805-A1 | OPTICAL PRODUCT PREPARED FROM HIGH INDEX OF REFRACTION BROMINATED MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | ERG28, UGCG, DPM1 | GABRA1 4267/4885GABRB1 4177/4885CYP3A4 3930/4885 |
| US-20050272949-A1 | High refractive index pressure-sensitive adhesives | ICAM1, CDH1, EPCAM | GABRA1 2138/4885GABRB1 3326/4885CYP3A4 4662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.