SCHEMBL7735689

SCHEMBL7735689

Cc1cc(C(C)(C)C)cc(C)c1C(=O)C(OCCOP=O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
ALDH1A1 P00352 2/20 0.35
PPARA Q07869 2/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
CYP3A4 P08684 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TACR1 P25103 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KEAP1 Q14145 2/20 0.33
NFE2L2 Q16236 2/20 0.33
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
CASP3 P42574 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7183312 0.89 LMNA (0.38) LMNAALDH1A1PPARAGAAHTT
SCHEMBL7181535 0.87 L3MBTL1 (0.40) LMNAALDH1A1PPARAGAAHTT
SCHEMBL7177121 0.79 TRPM4 (0.38) LMNAALDH1A1PPARAGAACYP3A4
SCHEMBL7181341 0.77 CA12 (0.42) LMNAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7181149 0.77 HPGD (0.39) ALDH1A1GAACYP3A4MEN1KMT2A
SCHEMBL7187015 0.76 ALDH1A1 (0.35) ALDH1A1GAACYP3A4CYP1A2CYP2C9
SCHEMBL20997310 0.75 LMNA (0.39) LMNAALDH1A1PPARAGAAHTT
SCHEMBL19514211 0.74 LMNA (0.33) LMNAALDH1A1PPARAGAAHTT
SCHEMBL7183330 0.73 CYP1A2 (0.37) LMNAALDH1A1PPARACYP3A4CYP1A2
SCHEMBL7183772 0.73 CYP1A2 (0.37) LMNAALDH1A1CYP3A4CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 LMNA 3247/4885ALDH1A1 3984/4885PPARA 2624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.