Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090705 | 0.87 | RAB9A (0.59) | RAB9AHTTLMNAMAPK1KMT2A | |
| SCHEMBL2894292 | 0.75 | LMNA (0.47) | RAB9AHTTLMNAMAPK1AR | |
| SCHEMBL5520271 | 0.74 | RAB9A (0.61) | RAB9AHTTLMNAMAPK1CES2 | |
| SCHEMBL28217099 | 0.73 | HTT (0.76) | RAB9AHTTLMNAMAPK1KMT2A | |
| SCHEMBL8050011 | 0.73 | HTT (0.65) | RAB9AHTTLMNAMAPK1KMT2A | |
| SCHEMBL6131922 | 0.73 | ACHE (0.71) | RAB9AHTTLMNAMAPK1KMT2A | |
| SCHEMBL6167104 | 0.73 | HTT (0.52) | RAB9AHTTLMNAMAPK1KMT2A | |
| SCHEMBL7084274 | 0.72 | HTT (0.51) | RAB9AHTTLMNAMAPK1KMT2A | |
| SCHEMBL31493230 | 0.72 | HTT (1.00) | RAB9AHTTLMNAMAPK1ACHE | |
| SCHEMBL503994 | 0.72 | HTT (1.00) | RAB9AHTTLMNAMAPK1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6426360-B1 | ANTIARTHRITIC AGENTS | G D SEARLE & CO. | 2002-07-30 | — | — | US | disclosed |