Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 8/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL921640 | 0.77 | KMT2A (0.59) | KMT2ATSHRSMN1; SMN2HPGDPOLB | |
| SCHEMBL5543276 | 0.76 | ALDH1A1 (0.40) | KMT2ATSHRL3MBTL1RAB9A | |
| SCHEMBL9507549 | 0.76 | MAPK1 (0.64) | KMT2ATSHRSMN1; SMN2HPGDPOLB | |
| SCHEMBL15009607 | 0.74 | CYP1A2 (0.59) | KMT2ASMN1; SMN2HPGDPOLBMAPT | |
| SCHEMBL30435803 | 0.74 | KMT2A (0.68) | KMT2ATSHRSMN1; SMN2HPGDPOLB | |
| SCHEMBL11001462 | 0.74 | KMT2A (0.68) | KMT2ATSHRSMN1; SMN2HPGDPOLB | |
| SCHEMBL11351938 | 0.73 | MAPT (0.69) | KMT2ATSHRSMN1; SMN2HPGDMAPT | |
| SCHEMBL921136 | 0.73 | MAPT (0.57) | KMT2ATSHRSMN1; SMN2HPGDMAPT | |
| SCHEMBL10495486 | 0.72 | KMT2A (0.70) | KMT2ATSHRSMN1; SMN2HPGDPOLB | |
| SCHEMBL17440373 | 0.72 | KMT2A (0.70) | KMT2ATSHRSMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403633-B2 | USEFUL ANTIANGIOGENIC, ANTIARTHRITIC, ANTIINFLAMMATORY, ANTIRESTENOTIC, ANTIINVASIVE, ANTIMETASTIC, ANTIOSTEOPOROTIC, ANTIRETINOPATHIC, CONTRACEPTIVE AND TUMORISTATIC TREATMENT AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-06-11 | — | — | US | claimed |