SCHEMBL921640

SCHEMBL921640

Fc1[c]cccc1Oc1ccc(C(F)(F)F)cn1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.59
HPGD P15428 1/20 0.57
TSHR P16473 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
POLB P06746 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.49
MAPT P10636 2/20 0.49
MAPK1 P28482 1/20 0.45
LIPE Q05469 6/20 0.43
THRB P10828 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
LMNA P02545 1/20 0.41
BCHE P06276 1/20 0.40
MEN1 O00255 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17440373 0.79 KMT2A (0.70) KMT2AHPGDTSHRSMN1; SMN2POLB
SCHEMBL7736113 0.77 KMT2A (0.55) KMT2AHPGDTSHRSMN1; SMN2POLB
SCHEMBL10495486 0.76 KMT2A (0.70) KMT2AHPGDTSHRSMN1; SMN2POLB
SCHEMBL920481 0.76 CYP1A2 (0.63) KMT2AHPGDSMN1; SMN2POLBMAPT
SCHEMBL11337376 0.75 HPGD (0.69) KMT2AHPGDTSHRSMN1; SMN2POLB
SCHEMBL11001462 0.75 KMT2A (0.68) KMT2AHPGDTSHRSMN1; SMN2POLB
SCHEMBL30435803 0.75 KMT2A (0.68) KMT2AHPGDTSHRSMN1; SMN2POLB
SCHEMBL11114747 0.75 TSHR (0.76) KMT2AHPGDTSHRSMN1; SMN2POLB
SCHEMBL31360348 0.74 KMT2A (0.59) KMT2AHPGDTSHRSMN1; SMN2POLB
SCHEMBL920694 0.74 KDM4E (0.49) KMT2APOLBLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 KMT2A 2469/4885HPGD 1273/4885TSHR 2588/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 KMT2A 1924/4885HPGD 1474/4885TSHR 2777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.