Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731064 | 0.91 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL7723256 | 0.86 | CYP2C9 (0.55) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL7736257 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL7733873 | 0.82 | CYP2D6 (0.41) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL7733096 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL7734109 | 0.81 | GRIN2B (0.54) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL7732672 | 0.75 | ACHE (0.64) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL8117602 | 0.75 | CYP2D6 (0.41) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL7732684 | 0.74 | GRIN2B (0.40) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL7732339 | 0.72 | CYP2C9 (0.49) | ALDH1A1MEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407122-B1 | NEUROPROTECTIVE AGENTS, ANTIISCHEMIC, AND HYPERGLYCEMIC AGENTS; HUNTINGTON*S, PARKINSON*S, AND ALZHEIMER*S DISEASE;AMYOTROPHIC LATERAL SCLEROSIS TREATMENT; NERVOUS SYSTEM AND BRAIN DISORDERS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-06-18 | — | — | US | disclosed |