Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024606 | 0.94 | NPC1 (0.43) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7033730 | 0.88 | ALOX5 (0.34) | NPC1RAB9APOLBALOX5THRB | |
| SCHEMBL7736256 | 0.88 | THRB (0.40) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7031867 | 0.87 | NPC1 (0.42) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL29372447 | 0.86 | NPC1 (0.48) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL226076 | 0.86 | NPC1 (0.48) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7737134 | 0.85 | ALOX5 (0.41) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28684325 | 0.84 | NPC1 (0.50) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7027917 | 0.84 | THRB (0.36) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5200144 | 0.83 | ALDH1A1 (0.38) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924203-B1 | 2,2'-BIS(6-BENZOTRIAZOLYLPHENOL) COMPOUNDS, ULTRAVIOLET ABSORBERS COMPRISING THE SAME, COPOLYMERS CONTAINING THE SAME, AND POLYMER COMPOSITIONS CONTAINING THE SAME | OTSUKA CHEMICAL CO LTD (JP) | 2003-02-05 | — | — | EP | disclosed |
| US-6281313-B1 | 2,2′BIS(6-Benzotriazolylphenol) compound, ultraviolet ray absorber comprising the compound, copolymer containing the compound and polymer composition containing the compound | OTSUKA CHEMICAL CO., LTD. (JP) | 2001-08-28 | — | — | US | disclosed |
| US-6084104-A | FREE FROM VOLATILITY AND ELUTION PROBLEMS DURING POLYMERIZATION OR MOLDING; EXCELLENT IN ALKALI RESISTANCE, HEAT RESISTANCE; NOT COLORED WHERE ALKALIS OR METAL IONS ARE PRESENT; EXCELLENT ULTRAVIOLET ABSORPTIVITY; WEATHERING | OTSUKA CHEMICAL CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0924203-A1 | 2,2'-BIS(6-BENZOTRIAZOLYLPHENOL) COMPOUNDS, ULTRAVIOLET ABSORBERS COMPRISING THE SAME, COPOLYMERS CONTAINING THE SAME, AND POLYMER COMPOSITIONS CONTAINING THE SAME | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 1999-06-23 | — | — | EP | disclosed |