Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.39 |
| ▸ | NPC1 | O15118 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPR3 | P17342 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 3/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732052 | 0.75 | RAB9A (0.43) | RAB9ANPC1MEN1KMT2AHIF1A | |
| SCHEMBL7861048 | 0.71 | C3AR1 (0.44) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL7736280 | 0.68 | DAGLA (0.34) | MEN1KMT2AALDH1A1METAP2SMN1; SMN2 | |
| SCHEMBL7734004 | 0.68 | RAB9A (0.42) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL7857951 | 0.66 | PSMB5 (0.46) | RAB9ANPC1MEN1KMT2AHIF1A | |
| SCHEMBL25166947 | 0.65 | NPC1 (0.53) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL23466400 | 0.64 | AAK1 (0.46) | RAB9ANPC1MEN1KMT2ABACE1 | |
| SCHEMBL23466402 | 0.64 | AAK1 (0.46) | RAB9ANPC1MEN1KMT2ABACE1 | |
| SCHEMBL29758106 | 0.64 | AAK1 (0.46) | RAB9ANPC1MEN1KMT2ABACE1 | |
| SCHEMBL3403454 | 0.64 | KAT6A (0.60) | RAB9ANPC1MEN1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |