Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732173 | 0.89 | TRPM8 (0.36) | DAGLASLC7A5SMN1; SMN2CYSLTR2CYSLTR1 | |
| SCHEMBL7732052 | 0.75 | RAB9A (0.43) | METAP2MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7732335 | 0.73 | CES1 (0.49) | DAGLAMETAP2KMT2AMETAP1 | |
| SCHEMBL7735836 | 0.72 | SLC1A3 (0.40) | METAP2CTSSALDH1A1KMT2ACTSB | |
| SCHEMBL7861048 | 0.71 | C3AR1 (0.44) | CTSSCTSKMEN1ALDH1A1KMT2A | |
| SCHEMBL7736282 | 0.68 | RAB9A (0.39) | METAP2MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL21543942 | 0.68 | ALDH1A1 (0.39) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30430246 | 0.68 | ALDH1A1 (0.39) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7734004 | 0.68 | RAB9A (0.42) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7732103 | 0.68 | RAB9A (0.53) | MEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |