Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.78 |
| ▸ | NPC1 | O15118 | 3/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | RAD52 | P43351 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | MGLL | Q99685 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795359 | 0.91 | ALDH1A1 (0.94) | ALDH1A1KDM4ENPC1TP53RAB9A | |
| SCHEMBL13070626 | 0.90 | NPC1 (0.67) | ALDH1A1KDM4ENPC1TP53RAB9A | |
| SCHEMBL11147683 | 0.89 | ALDH1A1 (0.90) | ALDH1A1KDM4ENPC1TP53RAB9A | |
| SCHEMBL5334244 | 0.84 | ALDH1A1 (0.97) | ALDH1A1KDM4ENPC1TP53RAB9A | |
| SCHEMBL5925560 | 0.83 | NPC1 (0.73) | ALDH1A1KDM4ENPC1TP53RAB9A | |
| SCHEMBL14537720 | 0.83 | TSHR (0.75) | ALDH1A1KDM4ENPC1TP53RAB9A | |
| SCHEMBL13070618 | 0.82 | NPC1 (0.72) | ALDH1A1KDM4ENPC1TP53RAB9A | |
| SCHEMBL6893687 | 0.82 | ALDH1A1 (0.79) | ALDH1A1KDM4ENPC1TP53RAB9A | |
| SCHEMBL27402246 | 0.82 | GAA (0.77) | ALDH1A1KDM4ENPC1TP53RAB9A | |
| SCHEMBL22777886 | 0.81 | KDM4E (0.94) | ALDH1A1KDM4ENPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410792-B1 | OBESITY DISEASES | BAYER CORPORATION | 2002-06-25 | — | — | US | disclosed |