Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | RARA | P10276 | 5/20 | 0.40 |
| ▸ | RARG | P13631 | 5/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27967750 | 0.83 | FABP4 (0.50) | AKR1C2AKR1C1MCL1MYCDHODH | |
| SCHEMBL7736036 | 0.81 | RARB (0.43) | RARBRARARARGAKR1C2AKR1C1 | |
| SCHEMBL7737091 | 0.77 | RARB (0.46) | RARBRARARARGAKR1C2AKR1C1 | |
| SCHEMBL7737127 | 0.76 | RARB (0.45) | RARBRARARARGMCL1RXRA | |
| SCHEMBL7737301 | 0.75 | NOTUM (0.37) | KMODHODH | |
| SCHEMBL489533 | 0.74 | HPGD (0.55) | MCL1RXRARXRBMYCADRA2A | |
| SCHEMBL7736415 | 0.73 | NOTUM (0.41) | RARBRARARARGAKR1C2AKR1C1 | |
| SCHEMBL7736417 | 0.73 | NOTUM (0.41) | RARBRARARARGAKR1C2AKR1C1 | |
| SCHEMBL4728958 | 0.73 | KDM4E (0.46) | RXRARXRBMYCADRA2ACLCN2 | |
| SCHEMBL7739027 | 0.73 | RXRA (0.36) | RARBRARARARGAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468606-B1 | LOW VISCOSITY, HIGH DIELECTRIC ANISOTROPY, LOW OPTICAL ANISOTROPY, EXCELLENT LOW TEMPERATURE COMPATIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUNDS; 3,4,5-TRIFLUOROPHENYL-(2-FLUORO-4-(TRANS-4-PROPYLCYCLOHEXYL))BENZOATE | CHISSO CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0808825-B1 | PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS | CHISSO CORP (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5922243-A | LOW VISCOSITY, HIGH DIELECTRIC AND LOW OPTICAL ANISOTROPY, EXCELLENT COMPATIBILITY | CHISSO CORPORATION (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0808825-A1 | PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS | CHISSO CORPORATION (JP) | 1997-11-26 | — | — | EP | disclosed |