SCHEMBL7737208

SCHEMBL7737208

CC1=C(C)C([Si](C)(C)NC2CCCCC2)c2cc3c(cc21)CCC3

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
OPRK1 P41145 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7743273 0.82 RAB9A (0.34) MEN1LMNAHPGDKMT2A
SCHEMBL7949383 0.78
SCHEMBL7745069 0.77 CDC25B (0.32)
SCHEMBL7741876 0.76 MEN1 (0.32) MEN1LMNAHPGDKMT2A
SCHEMBL7742391 0.72 TAS1R3 (0.38) MEN1KMT2A
SCHEMBL8024127 0.71 TAS1R3 (0.37) MEN1KMT2A
SCHEMBL6903828 0.68
SCHEMBL7944258 0.66 CDC25B (0.35)
SCHEMBL31231441 0.58
SCHEMBL9180883 0.55 ALDH1A1 (0.45) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420507-B1 COORDINATION CATALYSTS FOR POLYMERS THE DOW CHEMICAL COMPANY 2002-07-16 US disclosed
EP-0946575-B1 FUSED RING SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS DOW CHEMICAL CO (US) 2001-10-10 EP disclosed
US-6034022-A COORDINATION POLYMERIZATION CATALYST THE DOW CHEMICAL COMPANY (US) 2000-03-07 US disclosed
US-5965756-A COORDINATION CATALYSTS AS ADDITION POLYMERIZATION CATALYSTS THE DOW CHEMICAL COMPANY (US) 1999-10-12 US disclosed
EP-0946575-A1 FUSED RING SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1999-10-06 EP disclosed
WO-1998027103-A1 FUSED RING SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1998-06-25 WO disclosed