Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738427 | 0.81 | NR1H2 (0.53) | NR1H2NR1H3MAPTALDH1A1KMT2A | |
| SCHEMBL7739199 | 0.81 | HPGD (0.55) | NR1H2NR1H3MAPTALDH1A1CA1 | |
| SCHEMBL8836682 | 0.78 | NR1H2 (0.63) | NR1H2NR1H3MAPT | |
| SCHEMBL11314154 | 0.76 | MAPT (0.55) | MAPTALDH1A1CA1CA2TDP1 | |
| SCHEMBL254228 | 0.75 | CA1 (0.59) | MAPTALDH1A1CA1CA2TDP1 | |
| SCHEMBL16758244 | 0.73 | CA1 (0.57) | MAPTALDH1A1CA1CA2TDP1 | |
| SCHEMBL10522173 | 0.73 | NR1H2 (0.59) | NR1H2NR1H3MAPTALDH1A1CA1 | |
| SCHEMBL1427802 | 0.73 | LOXL2 (0.59) | MAPTALDH1A1CA1CA2TDP1 | |
| SCHEMBL2705494 | 0.73 | SNCA (0.58) | MAPTALDH1A1CA1CA2TDP1 | |
| SCHEMBL7732393 | 0.72 | NR1H2 (0.50) | NR1H2NR1H3ALDH1A1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |