Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738427 | 0.86 | NR1H2 (0.53) | HPGDNR1H2NR1H3TSHRALDH1A1 | |
| SCHEMBL8836682 | 0.82 | NR1H2 (0.63) | NR1H2NR1H3MAPT | |
| SCHEMBL9651811 | 0.81 | NR1H2 (0.56) | HPGDNR1H2NR1H3MAPT | |
| SCHEMBL7737542 | 0.81 | NR1H2 (0.49) | HPGDNR1H2NR1H3TSHRALDH1A1 | |
| SCHEMBL7732393 | 0.79 | NR1H2 (0.50) | HPGDNR1H2NR1H3TSHRALDH1A1 | |
| SCHEMBL10522173 | 0.77 | NR1H2 (0.59) | HPGDNR1H2NR1H3TSHRTP53 | |
| SCHEMBL1147728 | 0.77 | NR1H2 (0.53) | NR1H2NR1H3TSHRALDH1A1L3MBTL1 | |
| SCHEMBL7740910 | 0.76 | NPC1 (0.48) | HPGDNR1H2NR1H3TSHRALDH1A1 | |
| SCHEMBL10941257 | 0.75 | NR1H2 (0.56) | HPGDNR1H2NR1H3TP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL1680325 | 0.74 | ALDH1A1 (0.58) | HPGDTSHRTP53ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |