Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734098 | 0.94 | LTB4R (0.40) | PTPN1TLR7THRATHRBHDAC8 | |
| SCHEMBL27607975 | 0.86 | CCNC (0.48) | PTPN1TLR7THRATHRBCNR2 | |
| SCHEMBL7737488 | 0.83 | PTPN1 (0.44) | PTPN1THRATHRBHDAC8AKR1C3 | |
| SCHEMBL7735380 | 0.82 | PTPN1 (0.44) | PTPN1THRATHRBHDAC8AKR1C3 | |
| SCHEMBL3889870 | 0.82 | CCNC (0.48) | PTPN1ALOX5 | |
| SCHEMBL27402110 | 0.81 | LTB4R (0.43) | HDAC8LTB4RPPARGPPARAALOX5 | |
| SCHEMBL7735407 | 0.81 | TRPV1 (0.43) | CNR2CNR1PPARGPPARAALOX5 | |
| SCHEMBL27627133 | 0.81 | CCNC (0.49) | PTPN1ALOX5 | |
| SCHEMBL7725111 | 0.81 | PTPN1 (0.56) | PTPN1TLR7THRATHRBAKR1C3 | |
| SCHEMBL7725159 | 0.80 | THRA (0.47) | PTPN1THRATHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | disclosed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |