SCHEMBL7735407

SCHEMBL7735407

CCCCOc1c(OC)cc(CCCC(=O)OC)cc1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.43
SLC6A5 Q9Y345 1/20 0.42
POLB P06746 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
HPGD P15428 2/20 0.41
ALOX5 P09917 1/20 0.41
PPARG P37231 3/20 0.41
PPARA Q07869 2/20 0.41
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
TNKS2 Q9H2K2 2/20 0.40
PLAAT3 P53816 1/20 0.40
PLAAT5 Q96KN8 1/20 0.40
PLAAT2 Q9NWW9 1/20 0.40
PLAAT4 Q9UL19 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7725105 0.91 FFAR4 (0.46) TRPV1SLC6A5PPARGPPARATNKS2
SCHEMBL7734098 0.87 LTB4R (0.40) CNR1CNR2PPARGPPARA
SCHEMBL7725078 0.84 GABRA1 (0.40) POLBCNR1CNR2PPARGPPARA
SCHEMBL7734892 0.83 HDAC8 (0.39) CNR1CNR2PPARGPPARA
SCHEMBL7735710 0.83 ALDH1A1 (0.45) CNR2PPARG
SCHEMBL7737515 0.83 THRA (0.49) HPGDALOX5PPARGPPARAPLAAT3
SCHEMBL7733973 0.83 THRA (0.49) SLC6A5HPGD
SCHEMBL7735362 0.83 PTPN1 (0.39) TRPV1CNR1CNR2HPGD
SCHEMBL7737564 0.81 PTPN1 (0.45) CNR1CNR2ALOX5PPARGPPARA
SCHEMBL7737650 0.80 THRA (0.53) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed