Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 19/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735164 | 0.89 | NLRP3 (0.35) | MTNR1AMTNR1BPTGER1 | |
| SCHEMBL7733869 | 0.80 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| SCHEMBL5098194 | 0.78 | ALDH1A1 (0.45) | — | |
| SCHEMBL7734094 | 0.75 | MEN1 (0.39) | MTNR1AMTNR1B | |
| SCHEMBL7724837 | 0.72 | PTK2 (0.41) | MTNR1AMTNR1B | |
| SCHEMBL8903484 | 0.70 | NQO2 (0.55) | MTNR1A | |
| SCHEMBL4852971 | 0.70 | TAAR1 (0.46) | — | |
| SCHEMBL21684354 | 0.69 | ELANE (0.43) | MTNR1AMTNR1B | |
| SCHEMBL1924989 | 0.68 | KDM4E (0.47) | — | |
| SCHEMBL7734337 | 0.68 | NLRP3 (0.36) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |