Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737657 | 0.89 | MTNR1A (0.43) | PTGER1MTNR1AMTNR1B | |
| SCHEMBL7734094 | 0.87 | MEN1 (0.39) | NLRP3LMNAMAPTMTNR1AMTNR1B | |
| SCHEMBL7734337 | 0.82 | NLRP3 (0.36) | NLRP3LMNAMAPTMTNR1AMTNR1B | |
| SCHEMBL7734700 | 0.80 | NLRP3 (0.35) | NLRP3LMNAMAPTMTNR1AMTNR1B | |
| SCHEMBL7734340 | 0.77 | ATM (0.41) | NLRP3PTGER1LMNAMAPTAKR1B1 | |
| SCHEMBL5098194 | 0.76 | ALDH1A1 (0.45) | LMNAKDM4EALDH1A1 | |
| SCHEMBL7733885 | 0.74 | ESR1 (0.39) | NLRP3LMNAMAPTAKR1B1KDM4E | |
| SCHEMBL7724834 | 0.73 | L3MBTL1 (0.39) | NLRP3LMNAMAPTAKR1B1KDM4E | |
| SCHEMBL7734093 | 0.73 | SIRT2 (0.37) | MAPTMTNR1AMTNR1BAKR1B1SSTR2 | |
| SCHEMBL7734855 | 0.70 | SIRT2 (0.34) | MTNR1AMTNR1BAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |