Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738147 | 0.89 | ALDH1A1 (0.81) | ALDH1A1HPGDNPC1USP2LMNA | |
| SCHEMBL7735928 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HPGDNPC1USP2LMNA | |
| SCHEMBL7735984 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HPGDNPC1USP2SMN1; SMN2 | |
| SCHEMBL9921691 | 0.79 | ATM (0.76) | ALDH1A1HPGDNPC1USP2LMNA | |
| SCHEMBL12598071 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HPGDNPC1USP2LMNA | |
| SCHEMBL13025526 | 0.78 | ATM (0.74) | ALDH1A1HPGDNPC1USP2LMNA | |
| SCHEMBL6555426 | 0.78 | ALDH1A1 (0.80) | ALDH1A1HPGDNPC1USP2LMNA | |
| SCHEMBL403057 | 0.78 | ATM (0.74) | ALDH1A1HPGDNPC1USP2LMNA | |
| SCHEMBL3216808 | 0.78 | ATM (0.74) | ALDH1A1HPGDNPC1USP2LMNA | |
| SCHEMBL7735766 | 0.78 | SMN1; SMN2 (0.64) | ALDH1A1HPGDNPC1USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410792-B1 | OBESITY DISEASES | BAYER CORPORATION | 2002-06-25 | — | — | US | claimed |
| US-6410792-B1 | OBESITY DISEASES | BAYER CORPORATION | 2002-06-25 | — | — | US | disclosed |