Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738147 | 0.85 | ALDH1A1 (0.81) | ALDH1A1HPGDNPC1USP2RAD52 | |
| SCHEMBL7736310 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HPGDNPC1USP2NPSR1 | |
| SCHEMBL7735766 | 0.81 | SMN1; SMN2 (0.64) | ALDH1A1HPGDNPC1USP2NPSR1 | |
| SCHEMBL7738167 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HPGDNPC1USP2MAPK1 | |
| SCHEMBL3305614 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HPGDNPC1USP2NPSR1 | |
| SCHEMBL1181160 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HPGDNPC1USP2NPSR1 | |
| SCHEMBL7735928 | 0.77 | ALDH1A1 (0.71) | ALDH1A1HPGDNPC1USP2RAD52 | |
| SCHEMBL7736314 | 0.76 | ALDH1A1 (0.62) | ALDH1A1HPGDNPC1USP2DRD4 | |
| SCHEMBL8155606 | 0.76 | SMN1; SMN2 (0.81) | ALDH1A1HPGDNPC1USP2DRD4 | |
| SCHEMBL8140676 | 0.75 | ALDH1A1 (0.58) | ALDH1A1HPGDNPC1USP2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410792-B1 | OBESITY DISEASES | BAYER CORPORATION | 2002-06-25 | — | — | US | disclosed |