Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | ME2 | P23368 | 1/20 | 0.61 |
| ▸ | ME1 | P48163 | 1/20 | 0.61 |
| ▸ | ME3 | Q16798 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | RAD52 | P43351 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738147 | 0.85 | ALDH1A1 (0.81) | ALDH1A1NPC1USP2HPGDMAPT | |
| SCHEMBL7738167 | 0.83 | ALDH1A1 (1.00) | ALDH1A1NPC1USP2HPGDLMNA | |
| SCHEMBL7735766 | 0.81 | SMN1; SMN2 (0.64) | ALDH1A1NPC1USP2HPGDMAPT | |
| SCHEMBL13780694 | 0.80 | ALDH1A1 (0.51) | ALDH1A1NPC1USP2HPGDMAPT | |
| SCHEMBL7726594 | 0.79 | ALDH1A1 (0.61) | ALDH1A1NPC1USP2HPGDLMNA | |
| SCHEMBL7738099 | 0.78 | ALDH1A1 (0.59) | ALDH1A1NPC1USP2HPGDLMNA | |
| SCHEMBL3305614 | 0.77 | ALDH1A1 (0.61) | ALDH1A1NPC1USP2HPGDLMNA | |
| SCHEMBL8140676 | 0.77 | ALDH1A1 (0.58) | ALDH1A1NPC1USP2HPGDMAPT | |
| SCHEMBL7735984 | 0.77 | ALDH1A1 (0.67) | ALDH1A1NPC1USP2HPGDMAPT | |
| SCHEMBL17730978 | 0.76 | DRD2 (0.68) | ALDH1A1NPC1USP2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410792-B1 | OBESITY DISEASES | BAYER CORPORATION | 2002-06-25 | — | — | US | disclosed |