Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273842 | 0.91 | DRD2 (0.47) | DRD2GNAO1 | |
| SCHEMBL23806855 | 0.85 | DRD2 (0.43) | DRD2SMN1; SMN2GNAO1 | |
| SCHEMBL7738185 | 0.83 | HSD11B1 (0.47) | ACHECYP1A2CHRM5ADRA2CSMN1; SMN2 | |
| SCHEMBL24146232 | 0.81 | CYP1A2 (0.42) | ACHECYP1A2CHRM5ADRA2C | |
| SCHEMBL23867015 | 0.80 | GNAO1 (0.58) | DRD2GNAO1 | |
| SCHEMBL24723958 | 0.79 | CHRM5 (0.61) | ACHECYP1A2CHRM5ADRA2CSMN1; SMN2 | |
| SCHEMBL13606801 | 0.79 | CYP1A2 (0.50) | ACHECYP1A2CHRM5ADRA2CALDH1A1 | |
| SCHEMBL28750905 | 0.79 | CHRM5 (0.40) | ACHECYP1A2CHRM5ADRA2CSMN1; SMN2 | |
| SCHEMBL18286778 | 0.79 | ALOX15 (0.48) | ACHECYP1A2CHRM5ADRA2CGNAO1 | |
| SCHEMBL27339213 | 0.79 | DRD2 (0.42) | DRD2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |