Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 2/20 | 0.60 |
| ▸ | MMP1 | P03956 | 5/20 | 0.59 |
| ▸ | MMP2 | P08253 | 4/20 | 0.59 |
| ▸ | MMP9 | P14780 | 4/20 | 0.59 |
| ▸ | MMP8 | P22894 | 4/20 | 0.59 |
| ▸ | MMP13 | P45452 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | BMP1 | P13497 | 2/20 | 0.57 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26769801 | 0.95 | MEP1B (0.65) | MEP1BMMP1MMP2MMP9MMP8 | |
| SCHEMBL25225813 | 0.87 | TAS2R14 (0.59) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL6411677 | 0.86 | MEP1B (0.79) | MEP1BMMP1MMP2MMP9MMP8 | |
| SCHEMBL25220429 | 0.86 | TAS2R14 (0.54) | MAPTTP53TAS2R14KMT2AMEN1 | |
| SCHEMBL25219555 | 0.82 | ALDH1A1 (0.58) | MAPTTP53TAS2R14KMT2AMEN1 | |
| SCHEMBL26769878 | 0.82 | MEP1B (0.66) | MEP1BMMP1MMP2MMP9MMP8 | |
| SCHEMBL10144135 | 0.81 | MAPT (0.64) | MAPTTP53THRBSMN1; SMN2LMNA | |
| SCHEMBL7348906 | 0.81 | MEP1B (0.86) | MEP1BMMP1MMP2MMP9MMP8 | |
| SCHEMBL7347286 | 0.79 | MMP3 (0.76) | MEP1BMMP1MMP2MMP9MMP8 | |
| SCHEMBL2845552 | 0.78 | MEP1B (0.68) | MEP1BMMP1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |