Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10258367 | 0.86 | HSP90AA1 (0.51) | ALDH1A1MAPTL3MBTL1HSP90AA1HSP90AB1 | |
| SCHEMBL6651599 | 0.83 | PIK3CD (0.41) | MAPTKDM4ARAB9ANPC1APLNR | |
| SCHEMBL6652918 | 0.78 | P4HTM (0.49) | ALDH1A1MAPTL3MBTL1TDP1LMNA | |
| SCHEMBL6650658 | 0.76 | KMT2A (0.45) | MAPTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL471340 | 0.74 | TDP1 (0.58) | ALDH1A1MAPTL3MBTL1TDP1KDM4A | |
| SCHEMBL1976065 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1HSP90AA1HSP90AB1 | |
| SCHEMBL30527044 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1HSP90AA1HSP90AB1 | |
| SCHEMBL6650491 | 0.74 | MAPK1 (0.56) | ALDH1A1MAPTL3MBTL1LMNAHPGD | |
| SCHEMBL29571426 | 0.74 | MAPK1 (0.56) | ALDH1A1MAPTL3MBTL1LMNAHPGD | |
| SCHEMBL6649788 | 0.74 | MAPT (0.41) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416979-B1 | MARASMIELLUS CULTURE PRODUCT; ANTIINFLAMMATORY AGENT, ANTIARTHRITIC AGENTS | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |