Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738427 | 0.77 | NR1H2 (0.53) | NR1H2NR1H3SMN1; SMN2MAPTHPGD | |
| SCHEMBL7739199 | 0.77 | HPGD (0.55) | NR1H2NR1H3SMN1; SMN2TDP1MAPT | |
| SCHEMBL7738390 | 0.76 | SMN1; SMN2 (0.32) | SMN1; SMN2TDP1 | |
| SCHEMBL9651811 | 0.73 | NR1H2 (0.56) | NR1H2NR1H3MAPTHPGD | |
| SCHEMBL7737542 | 0.73 | NR1H2 (0.49) | NR1H2NR1H3TDP1MAPTHPGD | |
| SCHEMBL7737551 | 0.73 | NR1H2 (0.39) | NR1H2NR1H3SMN1; SMN2MAPT | |
| SCHEMBL3959577 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2TDP1MAPTHPGD | |
| SCHEMBL2331029 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2TDP1MAPTHPGD | |
| SCHEMBL8836682 | 0.71 | NR1H2 (0.63) | NR1H2NR1H3MAPT | |
| SCHEMBL8653647 | 0.70 | ALDH1A1 (0.49) | SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |