Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 7/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.37 |
| ▸ | MET | P08581 | 6/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737134 | 0.91 | ALOX5 (0.41) | AKR1B10AKR1B1METALOX5 | |
| SCHEMBL7736865 | 0.90 | AKR1B10 (0.37) | AKR1B10AKR1B1METALOX5 | |
| SCHEMBL7739360 | 0.84 | TNKS2 (0.32) | LMNAATM | |
| SCHEMBL7736240 | 0.81 | POLB (0.33) | LMNAATM | |
| SCHEMBL7268057 | 0.80 | ALOX5 (0.44) | AKR1B10AKR1B1METALOX5EGFR | |
| SCHEMBL74867 | 0.79 | NPC1 (0.33) | — | |
| SCHEMBL7736241 | 0.78 | NPC1 (0.30) | — | |
| SCHEMBL74481 | 0.78 | NPC1 (0.33) | — | |
| SCHEMBL7736243 | 0.78 | MCL1 (0.30) | — | |
| SCHEMBL227536 | 0.78 | AKR1B10 (0.36) | AKR1B10AKR1B1METALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414100-B1 | COMPOUND HAVING EXTREMELY LOW VAPOR PRESSURE AND HIGH DECOMPOSITION TEMPERATURE; CROSSLINKING AGENT FOR WEATHER RESISTANT POLYMERS | OTSUKA CHEMICAL CO., LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1055669-A1 | BISBENZOTRIAZOLYLPHENOL COMPOUNDS, ULTRAVIOLET ABSORBER, ULTRAVIOLET-ABSORBING POLYMER, AND RESIN COMPOSITION AND COATING MATERIAL BOTH CONTAINING THESE | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2000-11-29 | — | — | EP | disclosed |