SCHEMBL227536

SCHEMBL227536

CC=CC(=O)OCCCc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 6/20 0.36
AKR1B1 P15121 6/20 0.36
GAA P10253 1/20 0.35
MET P08581 5/20 0.34
ALOX5 P09917 1/20 0.34
TLR8 Q9NR97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23493184 0.95 MET (0.34) AKR1B10AKR1B1GAAMETALOX5
SCHEMBL28906863 0.90 GAA (0.39) AKR1B10AKR1B1GAAMETALOX5
SCHEMBL7262236 0.90 ALOX5 (0.40) AKR1B10AKR1B1GAAMETALOX5
SCHEMBL7144226 0.88 ALOX5 (0.35) AKR1B10AKR1B1GAAMETALOX5
SCHEMBL7736865 0.88 AKR1B10 (0.37) AKR1B10AKR1B1METALOX5TLR8
SCHEMBL227535 0.85 GAA (0.33) GAATLR8
SCHEMBL29370220 0.85 GAA (0.33) GAATLR8
SCHEMBL29575584 0.85 GAA (0.36) AKR1B10AKR1B1GAAMET
SCHEMBL2798152 0.85 GAA (0.36) AKR1B10AKR1B1GAAMET
SCHEMBL21694047 0.84 ALOX5 (0.39) AKR1B10AKR1B1METALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139087-A1 COMPOUND, POLYMER, LIGHT STABILIZER COMPOSITION, RESIN COMPOSITION, COATING MATERIAL COMPOSITION, ARTICLE, SEALING MATERIAL, MOLDED ARTICLE, METHOD FOR PRODUCING WEATHER-RESISTANT RESIN COMPOSITION, AND METHOD FOR IMPROVING WEATHER RESISTANCE OF SYNTHETIC RESIN ADEKA CORPORATION (JP) 2026-05-21 US disclosed
EP-4745198-A1 RESIN COMPOSITION, MOLDED ARTICLE, RESIN ADDITIVE COMPOSITION, METHOD FOR PRODUCING RESIN COMPOSITION, METHOD FOR IMPROVING CRYSTALLINITY OF CRYSTALLINE RESIN, AND MATERIAL FOR RESIN ADDITIVE COMPOSITION ADEKA CORPORATION (JP) 2026-05-20 EP disclosed
US-12577355-B2 Polyester polymer compositions CELANESE SALES GERMANY GMBH (DE) 2026-03-17 US disclosed
US-12577376-B2 Molded articles with laser-formed pattern Celanese Interntaional Corporation (US) 2026-03-17 US disclosed
US-20260002014-A1 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF ADEKA CORPORATION (JP) 2026-01-01 US disclosed
EP-3578161-B1 METHOD FOR IMPROVING STORAGE STABILITY OF COSMETIC ADEKA CORP (JP) 2025-11-12 EP disclosed
US-12466938-B2 Resin additive composition, thermoplastic resin composition, and molded article thereof ADEKA CORPORATION (JP) 2025-11-11 US disclosed
US-12435205-B2 Resin composition and molded article thereof ADEKA CORPORATION (JP) 2025-10-07 US disclosed
EP-4130197-B1 FLAME RETARDANT COMPOSITION, FLAME-RESISTANT SYNTHETIC RESIN COMPOSITION, AND MOLDED BODY ADEKA CORP (JP) 2025-10-01 EP disclosed
US-20250282947-A1 Polyester Polymer Composition Containing Low Friction Aid CELANESE POLYMERS HOLDING, INC. 2025-09-11 US disclosed
EP-1266932-B1 GRANULAR COMPOSITE ADDITIVE FOR POLYOLEFIN, PROCESS FOR PRODUCING THE SAME, AND POLYOLEFIN COMPOSITION CONTAINING THE SAME ASAHI DENKA KOGYO KK (JP) 2006-01-18 EP disclosed
US-20050282995-A1 Polyester resin container with improved weatherability ASAHI DENKA CO., LTD. (JP) 2005-12-22 US disclosed
US-6787067-B2 NUCLEATING AGENT COMPRISING ALKALI METAL SALT OR HYDROXYALUMINUM SALT OF AN AROMATIC MONOCARBOXLYLIC ACID OR ACID AROMATIC PHOSPHORIC ESTER COMPOUND; PHENOLIC ANTIOXIDANT, AND POLYPROPYLENE; DUSTLESS ASAHI DENKA KOGYO K.K. (JP) 2004-09-07 US disclosed
US-20040099849-A1 Ultraviolet absorber for synthetic resin and synthetic resin composition containing the same ADEKA CORPORATION (JP) 2004-05-27 US disclosed
EP-1375582-A2 Nucleating agent and crystalline polymer composition containing the same Asahi Denka Co., Ltd. (JP) 2004-01-02 EP disclosed
US-20030236329-A1 Nucleating agent and crystalline polymer composition containing the same ASAHI DENKA CO., LTD. (JP) 2003-12-25 US disclosed
US-20030162870-A1 Flame-retardant resin composition ASAHI DENKA CO., LTD. (JP) 2003-08-28 US disclosed
US-20030125432-A1 Granular composite additive for polyolefin, process for producing the same, and polyolefin composition containing the same ADEKA CORPORATION (JP) 2003-07-03 US disclosed
EP-1304350-A1 Flame-retardant resin composition Asahi Denka Co., Ltd. (JP) 2003-04-23 EP disclosed
EP-1266932-A1 GRANULAR COMPOSITE ADDITIVE FOR POLYOLEFIN, PROCESS FOR PRODUCING THE SAME, AND POLYOLEFIN COMPOSITION CONTAINING THE SAME ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2002-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577376-B2 Molded articles with laser-formed pattern LAS1L, PIM2, YES1 AKR1B10 4697/4885AKR1B1 4632/4885GAA 2597/4885
US-12577355-B2 Polyester polymer compositions SMCHD1, PWWP2B, USP30 AKR1B10 4507/4885AKR1B1 4817/4885GAA 4531/4885
US-20260002014-A1 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF NXF1, NOP2, RTF1 AKR1B10 2537/4885AKR1B1 2563/4885GAA 3499/4885
US-20260139087-A1 COMPOUND, POLYMER, LIGHT STABILIZER COMPOSITION, RESIN COMPOSITION, COATING MATERIAL COMPOSITION, ARTICLE, SEALING MATERIAL, MOLDED ARTICLE, METHOD FOR PRODUCING WEATHER-RESISTANT RESIN COMPOSITION, AND METHOD FOR IMPROVING WEATHER RESISTANCE OF SYNTHETIC RESIN SEM1, RAD51, SUN2 AKR1B10 3324/4885AKR1B1 3100/4885GAA 2755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.