Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 7/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.37 |
| ▸ | MET | P08581 | 6/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739362 | 0.90 | AKR1B10 (0.37) | AKR1B10AKR1B1METALOX5 | |
| SCHEMBL7737134 | 0.90 | ALOX5 (0.41) | AKR1B10AKR1B1METALOX5NPC1 | |
| SCHEMBL227536 | 0.88 | AKR1B10 (0.36) | AKR1B10AKR1B1METALOX5TLR8 | |
| SCHEMBL7736862 | 0.84 | TLR8 (0.33) | TLR8NPC1RAB9ARXFP1 | |
| SCHEMBL7031951 | 0.82 | NPC1 (0.32) | AKR1B10AKR1B1ALOX5NPC1RAB9A | |
| SCHEMBL23493184 | 0.82 | MET (0.34) | AKR1B10AKR1B1METALOX5 | |
| SCHEMBL7737484 | 0.82 | POLB (0.33) | TLR8NPC1RAB9ARXFP1 | |
| SCHEMBL21693917 | 0.80 | APP (0.42) | AKR1B10AKR1B1METALOX5 | |
| SCHEMBL74862 | 0.79 | NPC1 (0.35) | TLR8NPC1RAB9ARXFP1 | |
| SCHEMBL7268057 | 0.79 | ALOX5 (0.44) | AKR1B10AKR1B1METALOX5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414100-B1 | COMPOUND HAVING EXTREMELY LOW VAPOR PRESSURE AND HIGH DECOMPOSITION TEMPERATURE; CROSSLINKING AGENT FOR WEATHER RESISTANT POLYMERS | OTSUKA CHEMICAL CO., LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1055669-A1 | BISBENZOTRIAZOLYLPHENOL COMPOUNDS, ULTRAVIOLET ABSORBER, ULTRAVIOLET-ABSORBING POLYMER, AND RESIN COMPOSITION AND COATING MATERIAL BOTH CONTAINING THESE | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2000-11-29 | — | — | EP | disclosed |