Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7740465 | 0.99 | KMT2A (0.36) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7734291 | 0.82 | NPC1 (0.32) | ALDH1A1MAPTNPC1MAPK1 | |
| Hydrochloric Acid SCHEMBL27514201 | 0.81 | NPC1 (0.31) | ALDH1A1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL7734154 | 0.81 | NPC1 (0.31) | ALDH1A1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL7738899 | 0.81 | RXFP1 (0.38) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL7742139 | 0.81 | AAK1 (0.40) | KMT2AMEN1ALDH1A1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL27512818 | 0.81 | TDO2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7740435 | 0.81 | TDO2 (0.32) | — | |
| SCHEMBL7740424 | 0.80 | MEN1 (0.36) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL7738922 | 0.77 | LMNA (0.32) | KMT2AMEN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1217928-C | Heterocyclic compound having NOS inhibitory action | CHUGAI SEIYAKA K K (JP) | 2005-09-07 | — | — | CN | claimed |
| US-6414005-B1 | BRAIN DISORDERS; ALZHEIMER'S DISEASE; PARKINSON'S DISEASE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-02 | — | — | US | claimed |
| CN-1280565-A | Heterocyclic compounds having NOS inhibitory activities | CHUGAI SEIYAKA K K (JP) | 2001-01-17 | — | — | CN | claimed |
| EP-1043312-A1 | HETEROCYCLIC COMPOUNDS HAVING NOS INHIBITORY ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-10-11 | — | — | EP | claimed |
| CN-1217928-C | Heterocyclic compound having NOS inhibitory action | CHUGAI SEIYAKA K K (JP) | 2005-09-07 | — | — | CN | disclosed |
| US-6414005-B1 | BRAIN DISORDERS; ALZHEIMER'S DISEASE; PARKINSON'S DISEASE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-02 | — | — | US | disclosed |
| CN-1280565-A | Heterocyclic compounds having NOS inhibitory activities | CHUGAI SEIYAKA K K (JP) | 2001-01-17 | — | — | CN | disclosed |
| EP-1043312-A1 | HETEROCYCLIC COMPOUNDS HAVING NOS INHIBITORY ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-10-11 | — | — | EP | disclosed |