Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747172 | 0.80 | QDPR (0.53) | QDPRMAPTAPPALOX5 | |
| SCHEMBL14320589 | 0.79 | F2 (0.38) | F2 | |
| SCHEMBL6646658 | 0.69 | TSHR (0.35) | F2 | |
| SCHEMBL10827686 | 0.66 | QDPR (0.69) | QDPRAPPALOX5 | |
| Hydrochloric Acid SCHEMBL10353907 | 0.65 | QDPR (0.67) | QDPRAPPALOX5 | |
| SCHEMBL7744628 | 0.64 | QDPR (1.00) | QDPRAPP | |
| SCHEMBL31367896 | 0.64 | QDPR (1.00) | QDPRAPP | |
| SCHEMBL7739767 | 0.61 | QDPR (1.00) | QDPRMAPTALDH1A1KMT2A | |
| SCHEMBL16581461 | 0.60 | QDPR (0.46) | QDPRMAPTAPPALOX5ACMSD | |
| SCHEMBL338028 | 0.59 | APP (1.00) | QDPRMAPTAPPALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730451-A4 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RES FOUNDATION INC (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-0730451-A1 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014468-A1 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RESEARCH FOUNDATION INC. (US) | 1995-06-01 | — | — | WO | disclosed |