Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 7/20 | 0.53 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.38 |
| ▸ | SNCA | P37840 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739762 | 0.80 | QDPR (0.47) | QDPRAPPALOX5MAPT | |
| SCHEMBL4790146 | 0.75 | NISCH (0.41) | QDPRMAPT | |
| SCHEMBL4789908 | 0.74 | PTGS1 (0.34) | QDPRMAPT | |
| SCHEMBL4790395 | 0.74 | SIGMAR1 (0.50) | — | |
| SCHEMBL578563 | 0.74 | HTR2C (0.50) | QDPRMAPT | |
| SCHEMBL4789903 | 0.72 | ADRA2A (0.41) | ALOX5 | |
| SCHEMBL4790265 | 0.72 | HTR2C (0.54) | — | |
| SCHEMBL5762608 | 0.72 | HSD17B1 (0.46) | — | |
| SCHEMBL10827686 | 0.72 | QDPR (0.69) | QDPRAPPALOX5SNCA | |
| SCHEMBL4790187 | 0.70 | CHRNB2 (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730451-A4 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RES FOUNDATION INC (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-0730451-A1 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014468-A1 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RESEARCH FOUNDATION INC. (US) | 1995-06-01 | — | — | WO | disclosed |